[DHB] Have You A Higher Risk Of Cancer?

Published: Tue, 06/24/14

Subject: [DHB] Have You A Higher Risk Of Cancer?

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June 24, 2014

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  • More Cancer Outcomes With Obesity
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More Cancer Outcomes With Obesity

Dear Reader,

Now you have even more reason to lose weight, especially if you've just been diagnosed with cancer. Experts know that obese patients have a risk of getting several different types of cancer, but a new bit of research released in advance of the American Society of Clinical Oncology annual meeting has found that being obese also ups the risk that cancer may come back for some people, and ups the chances these people will die from this disease.

We all know that smoking and cancer are linked, but fewer people think about the danger to the body of carrying all that extra weight. Yet in the last several decades, the number of overweight or obese people (including kids) has gone up drastically. Obesity may well, one day, replace tobacco as the leading cause for cancer deaths. Experts have already found obesity is associated with higher risk of cancers of the esophagus, breast, endometrium, colon and rectum, kidney, pancreas, thyroid, gallbladder and perhaps others as well. As if cancer wasn't enough, obese people are also at increased risk of coronary heart disease, stroke, high blood pressure, diabetes and a number of different chronic, life-altering diseases.

When it comes to weight and cancer, here's what we know...

- High birth weight is linked to higher cancer risk.

- Gaining weight during adulthood is linked to a higher risk of several cancers.

- Gaining and losing repeatedly may also be a cancer risk factor.

The current project on obesity and cancer included 80,000 patients in 70 different trials on early breast cancer and body mass index (BMI) estrogen receptor, menopause status, cancer recurrence and the prognosis each patient was given. They compared those with high BMIs (over 30.0) with subjects who had a normal BMI (18.5 to 24.9) over a decade long period. The team saw that for younger, pre menopausal women who had early stage cancer of the breast, obesity appears to be strongly linked to poorer outcomes, up to and including death.

Those with BMIs over 30.0 had a 21.5% chance of dying, while women with average BMIs had a 16.6% chance of death. This only applies to those who had hormone receptor positive breast cancer; there was no effect of obesity in those who had the negative estrogen receptor form of disease.


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More Cancer Outcomes With Obesity Continued...



These findings support the current thinking of healthcare professionals - women need to maintain a healthy body weight following being diagnosed with breast cancer. Doctors may also want to more closely monitor obese women who are premenopausal, and encourage them to move toward a more healthy weight.

One reason obesity is such a problem is because it does cause inflammation all through the body. The inflammation may activate the aromatase gene, which is responsible for converting estrogen and this hormone is known to fuel cancer growth in the hormone receptor positive form of disease. Obese people also have more fat, hormone producing tissue and this can be involved in the growth of cancer.

There is a lot more to understand in terms of breast cancer and obesity. One thing to recognize right now is that carrying too much weight is not good for you. It keeps you couch bound, has you feeling awful and puts you at risk for serious diseases. Losing the weight is possible, but it won't come quickly or easily - anyone who tells you differently is not being honest. That does not mean change isn't possible and sustainable for you as it has been for others. Tap into the resources around you, including your own doctor or a dietitian.

To your good health,

Kirsten Whittaker
Daily Health Bulletin Editor




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Sources:
http://thechart.blogs.cnn.com/2014/05/16/obesity-may-affect-cancer-patients-outcomes/

Breastcancer.org info on hormone receptor status in breast cancer:
http://www.breastcancer.org/symptoms/diagnosis/hormone_status

National Cancer Institute info on obesity and cancer:
http://www.cancer.gov/cancertopics/factsheet/Risk/obesity

















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