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August 3, 2009
In Today's Issue
- Overweight? Shocking Proof that it may not be your fault
- Swine Flu Vaccine Taking Longer Than Expected
- Announcing: Doctor Approved Store Cupboard Remedies that Really Work...
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Swine Flu Vaccine Taking Longer Than Expected
Dear Reader,
Vaccine making is not an easy process.
Each February experts make a decision about what type of flu vaccine
to produce for the upcoming season and as you might imagine, this year's
outbreak of A (H1N1) or swine flu has disrupted that schedule a bit.
And while seasonal flu vaccine is still being made, it's hard for the
current vaccine producing system to shift gears fast enough, and the
technology being used isn't as modern as we might like.
While the first trial vaccines are expected within a few weeks, it may
not be until the end of this year that a fully tested swine flu vaccine
is ready according to the World Health Organization (WHO).
An already difficult vaccine production process is made worse by the
swine flu viruses being used to develop the vaccine.
It seems they're
only offering half as much "yield" in egg-based production
(most of today's vaccine is made this way) as what manufacturer's get
when creating vaccine for the seasonal flu virus.
U.S. health officials are said to be considering a swine flu immunization
program that involves an astonishing 600 million doses. Who will administer
the vaccine, and how side effects will be tracked has yet to be determined.
The good news is that swine flu, known officially as A (H1N1), remains
a relatively mild illness and the vast majority of patients continue
to recover quickly.
The virus is still susceptible to antiviral drugs, including Tamiflu,
which makes these medicines ideal as a treatment option for infected
patients.
On the down side, research does suggest that A (H1N1) causes more lung
damage than the seasonal flu strain.
It's also important to know that
this A (H1N1) strain is able to take the life of the young and previously
healthy.
In fact, almost half of those who've died worldwide have been
just that. By contrast, the seasonal flu is usually most deadly to
the very young or the very old.
In a piece on the A (H1N1) flu appearing in the journal Nature, University
of Wisconsin-Madison scientist Yoshihiro Kawaoka and colleagues took
virus samples from patients infected with the A (H1N1) swine flu and
looked at how they affected different animals.
In mice, ferrets and monkeys, the A (H1N1) swine flu virus brought on
lung conditions that were more severe than seen in the seasonal flu.
Researchers think this might explain why A (H1N1) has caused some serious
cases of pneumonia in those who were otherwise healthy.
The A (H1N1) swine flu arrived in the U.S. in the middle of April, and
estimates have about one million Americans being infected though there
are far fewer "confirmed" cases.
There continue to be deaths from the illness.
The Wisconsin researchers
also found that A (H1N1) is closely related to the viruses that were
behind the devastating 1918-1919 Spanish flu pandemic. In fact, antibodies
taken from those born before 1920 recognize the current swine flu virus,
not so for those born after 1920.
What worries health officials today is that the virus we know now might
mutate into a more virulent and dangerous illness.
Continues below...
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Swine Flu Vaccine Taking Longer Than Expected Continued...
While we continue to wait for a vaccine to arrive, it's important to look
back at the last large-scale government-backed swine flu vaccination campaign
in 1976. In hindsight a program that earned mixed reviews.
It was an incredible mobilization of the nations health care system, though
a miserable failure after a paralyzing nerve disorder known as Guillain-Barre
syndrome struck 500 (and killed 30) of those who'd been vaccinated.
It wasn't until December 1976 that federal officials canceled the program,
though not before 40 million Americans were inoculated against a pandemic that
in the end never materialized.
Perhaps the lessons learned from this, as well as the WHO decree that before
a country can start a large-scale vaccination program the vaccines used need
to be checked for safety by regulators, will help future efforts improve on
past ones.
To your good health,
Kirsten Whittaker
Daily Health Bulletin Editor
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Sources:
http://www.forbes.com/feeds/hscout/2009/07/13/
hscout628989.html?feed=rss_forbeslife_health
CDC info on A (H1N1):
http://cdc.gov/h1n1flu/
World Health Organization info on swine flu:
http://www.who.int/csr/disease/swineflu/en/index.html
Info on vaccine production:
http://www.crainsnewyork.com/article/20090428/PULSE/904279965
The journal Nature:
http://www.nature.com/nature/index.html
Abstract (login and fee required to read full text) in the
journal Nature:
http://www.nature.com/nature/journal/v459/n7249/full/nature08157.html
Forbes article on U.S. immunization plans:
http://www.forbes.com/feeds/hscout/2009/06/26/hscout628511.html
Story on President Ford and the 1976 swine flu immunization
program:
http://www.wired.com/science/discoveries/news/2008/03/dayintech_0324
Exceptional info on flu pandemic of 1918-1919:
http://virus.stanford.edu/uda/
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