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April 23, 2010
In Today's Issue
- 1 Quick Technique To Burn More Fat
- Fluctuating Blood Pressure Increases Stroke Risk...
- No Gym Bodyweight Workouts For Your Best Body Ever
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Fluctuating Blood Pressure Increases Stroke Risk...
Dear Reader,
High blood pressure patients take note... findings released in March 2010 at the American College of Cardiology (ACC) annual meeting in Atlanta have some pretty important implications for those who are trying to manage their condition.
A large five-year study finds that fluctuations in blood pressure over time may be a key indicator of stroke risk.
In the research, a British team of experts tracked the health of over 19,000 patients who were taking either beta blockers or calcium channel blocker medications to manage high blood pressure.
Patients who were in the highest 10% in terms of swings in blood pressure readings between visits to the doctor had almost four times the risk of stroke as those whose blood pressure didn't vary so much. The results were the same when the researchers looked at the subjects' risks for heart attack.
Subjects who took calcium channel blockers had a 22% lower risk of stroke vs. those who took beta blocker medications. The differences in blood pressure readings between the two groups seemed to explain the difference in risk.
In an ACC news release, study author Dr. Peter Sever, a clinical pharmacology and therapeutics professor and co-director of the International Centre for Circulatory Health, Imperial College, London says, "Our data convincingly demonstrate that patients with more variation in their blood pressure levels are at greatest risk of future heart attacks and strokes, and that reducing variability is a key goal of treatment."
This research findings echo those of a total of four other studies published in The Lancet and The Lancet Neurology led by Dr. Peter Rothwell of the University of Oxford in England. Rothwell and his team found that those with the biggest variation in systolic blood pressure (the top number) over seven visits to their doctor were six times more likely to have a major stroke. Earlier work had looked at short-term variability (24 hours) but this time the researchers examined visit-to-visit variability of readings. Those with the highest blood pressure readings were a whopping 15 times more likely to suffer a stroke.
Everyone is now wondering if recommendations for the treatment of high blood pressure should change.
To date most doctors haven't been too concerned about variation in blood pressure readings, or the maximum pressure reading for a patient, but this could change based on the latest research.
It may well be that random variations in blood pressure cannot be ignored as they're telling you something about risk.
This might be especially important if you're over 55 years old, the age group that makes up 80% of those with hypertension.
The take home message is this...
Continues below...
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Fluctuating Blood Pressure Increases Stroke Risk... Continued...
"Today, most hypertension guidelines recommend avoiding use of beta blockers
as first-line drugs if there is no other compelling indication," Carlberg and
Lindholm conclude in a comment in The Lancet.
"
The new analyses strengthen this recommendation and might prompt reconsideration
by those who keep beta blockers as first-line treatment. However, more studies
need to be done to better characterize the effects of different classes of antihypertensive
drugs on long-term blood-pressure variability."
More research will surely follow, but this work certainly should have you taking
your high blood pressure treatment seriously and talking to your doctor about
any variations in your own readings.
To your good health,
Kirsten Whittaker
Daily Health Bulletin Editor
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Sources:
http://www.medicinenet.com/script/main/art.asp?articlekey=114415
MedicineNet info on stroke:
http://www.medicinenet.com/stroke/article.htm
MedicineNet info on high blood pressure:
http://www.medicinenet.com/high_blood_pressure/article.htm
American Heart Association, high blood pressure info:
http://www.americanheart.org/presenter.jhtml?identifier=2114
MedicineNet info on beta blockers:
http://www.medicinenet.com/beta_blockers/article.htm
MedicineNet info on calcium channel blockers:
http://www.medicinenet.com/calcium_channel_blockers/article.htm
A heart.org article on study:
http://www.theheart.org/article/1058005.do
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