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February 4, 2011
In Today's Issue
- Weight Loss Expert Loses 70lbs of Ugly Fat...
- Assessing Breast Cancer Risk: Questions Your Doctor Isn't Asking...
- Announcing: Doctor Approved Store Cupboard Remedies that Really Work...
Weight Loss Expert Loses 70lbs of Ugly Fat...
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Assessing Breast Cancer Risk: Questions Your Doctor Isn't Asking...
Dear Reader,
Something for all women to think about. Just because breast cancer hasn't struck a woman in your family doesn't mean you're safe from the devastation of this disease.
A team of researchers tracking over 6,000 women for up to six years found that most cases of breast cancer happened in patients without a family history of disease, though these patients did have other factors that can predict a woman's likelihood of being diagnosed with cancer of the breast.
Yet the tendency to look for family history remains strong, and patients newly diagnosed often wonder how they developed the disease without a family history.
Earlier research has shown that over 70% of primary care physicians ask a woman about her family history, but less than half collect information on other known breast cancer risk factors like if periods started before age 12, or if she's given birth.
In the current study, funded by breast cancer treatment maker Eli Lily and Company, the research team analyzed the roles of various breast cancer risk factors among 6,322 postmenopausal women who had taken part in two large trials of osteoporosis drugs. All the subjects were all under 86 years old, and none had been diagnosed with breast cancer.
The researchers turned to the Breast Cancer Risk Assessment Tool, an online questionnaire that allowed them to go back in time and predict the odds that the women would develop the invasive disease over the next five years. The calculation incorporates age of first period, current age, ethnicity, reproductive history, earlier breast biopsies and family history. The score comes on a scale of zero to eight, and gives a percentage that represents a woman's five-year risk of breast cancer.
The most common known risk factors for breast cancer identified in the study include:
- Being at least 65 years old
- Starting menstruation before 12 years old
Just about 600 of the female subjects (one in ten) had a family history of breast cancer, and nearly all of them met the predictive tool's definition of high risk with a score of 1.66% or above. More than half of the remaining subjects who didn't have family histories also fit into the high-risk category. A total of 92 women, or 11.5% of the study population eventually developed invasive breast cancer over the follow up of 4 to 6 years.
Continues below...
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Assessing Breast Cancer Risk: Questions Your Doctor Isn't Asking... Continued...
The actual rate of breast cancer went up with the predicted risks, as well as
when a family history was present. Still, more of the total number of diagnosed
breast cancers of the subjects ended up being in women with predictions below
the high risk cut off, or without a family history. In other words, out of the
blue.
Close to half the women who were diagnosed with breast cancer had a risk score
below 1.66%, and nearly two of every three diagnosed women had been given risk
numbers between 1 and 2% and had no family history of breast cancer. The take
home message from the findings - the single largest risk factor for developing
breast cancer is being a woman; the second largest is being a woman over 50 years
old.
But, there are some women who are at greater risk than average, particularly
if you do have a family history. Medical professionals need to move beyond asking
about family history to assess the risk of breast cancer. This can identify women
at increased risk and allow them to take advantage of screening and prevention
strategies that might help.
Of course if you're worried about your own risk, family history or not, do all
you can to keep yourself healthy. Don't smoke. Eat a healthy diet. Maintain a
healthy weight. Exercise. Have regular screening tests.
To your good health,
Kirsten Whittaker
Daily Health Bulletin Editor
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Sources:
http://news.yahoo.com/s/nm/20101230/hl_nm/us_family_history
Breastcancer.org info on breast cancer:
http://www.breastcancer.org/
National Cancer Institute's Breast Cancer Risk Assessment Tool:
http://www.cancer.gov/bcrisktool/
Study abstract in Menopause, December 18, 2010:
http://medicine.journalfeeds.com/obgyn/menopause/estimated-risk-of-invasive-breast-cancer-in-postmenopausal-women-with-and-without-family-history-of-the-disease/20101225/
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