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November 28, 2011
In Today's Issue
- Weight Loss Expert Loses 70lbs of Ugly Fat...
- How A Healthy Diet Offsets Bad Genes For Heart Disease...
- Medical Doctor Reveals The Shocking Truth
Weight Loss Expert Loses 70lbs of Ugly Fat...
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How A Healthy Diet Offsets Bad Genes For Heart Disease...
Dear Reader,
Everyone knows that eating a very healthy diet is an important way to make heart disease less likely. Now a new study appearing in PLoS Medicine finds that even those who have genes that put them at a higher risk for heart problems can get the very same benefit from healthy eating.
So, enjoying all those good-for-you fruits and veggies can overcome your genetic
risk of heart attack.
Estimates are that almost 20% of the population has a copy of the "bad" heart gene according to Sonia S. Anand, MD, PhD, a professor of medicine at McMaster University in Canada and lead researcher on the latest study. She and her colleagues looked at how diet might affect variants in the chromosome 9p21 region.
Back in 2007 experts from different countries found that variants in this 9p21 area were associated with heart disease and more specifically, heart attack. Some of us have one copy of the gene; others have two, which is believed to make the risk of heart problems even greater.
Anand and her team examined the effects of a healthy (or unhealthy) eating plan on over 27,000 subjects of five ethnicities, Arab, Chinese, European, Latin American and South Asian. Some of the subjects were known to have high-risk genes.
In one group, from the INTERHEART study, 3,820 subjects who had heart attacks were compared with 4,294 who didn't. The FINRISK research provided the second group, 19,129 subjects, where 1,014 were known to have heart disease.
The INTERHEART research provided different diet information with diet scores based on raw veggie and fruit intake. The score also accounted for risk foods like fried foods, salty snacks and meat.
In the FINRISK study, diet details were collected from a questionnaire that had 130 food items. The score a participant received was based on their intake of fruit, veggies and berries. If you ate at least two out of those three items each day you were given the prudent rating.
If you had bad genes and ate the least prudent diet, heart disease risk increased almost 30%, but the risk of those who had the bad genotype but were part of the high prudent eating plan group saw no increased risk of heart attack.
This suggests that diet can make bad genes behave even more badly. The opposite also was shown to be true - the better the diet the lower the risk of disease.
Continues below...
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How A Healthy Diet Offsets Bad Genes For Heart Disease... Continued...
The take home message here is that even with bad genetics, you might still be
able to do something about them with a diet that's regularly loaded with prudent
choices like healthful fruits and veggies.
Interesting to realize that the choices you make, every single day at every single
meal, can have such an impact on your health. It's encouraging to realize that
maybe you can, if not change your genes at least make them less of a threat to
your health.
If the very solid research is supported by further work, it could have an impact
for many at risk of heart disease. The study also serves as the first evidence
in an emerging field known as nutrigenomics, or the study of the way our genes
interact with the nutrients in our diet.
To your good health,
Kirsten Whittaker
Daily Health Bulletin Editor
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Sources:
http://www.medicinenet.com/script/main/art.asp?articlekey=150409
MedicineNet info on heart disease:
http://www.medicinenet.com/heart_disease/article.htm
National Heart, Lung and Blood Institute on what is a heart attack:
http://www.nhlbi.nih.gov/health/health-topics/topics/heartattack/
More on INTERHEART Study:
http://www.medscape.com/viewarticle/489738
More on FINRISK Study:
http://www.ktl.fi/portal/english/research__people___programs/
health_promotion_and_chronic_disease_prevention/units/
chronic_disease_epidemiology_unit/the_national_finrisk_study
Wikipedia entry on nutrigenomics:
http://en.wikipedia.org/wiki/Nutrigenomics
Research article in PLoS Medicine, published 10/11/2011:
http://www.plosmedicine.org/article/info%3Adoi%2
F10.1371%2Fjournal.pmed.1001106
Sonia S. Anand, MD, PhD, a professor of medicine at McMaster University:
http://fhs.mcmaster.ca/ceb/faculty_member_anand.htm
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