[DHB] Fructose Linked With This Chronic Condition...

Published: Wed, 03/14/12

Subject: [DHB] Fructose Linked With This Chronic Condition...

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Daily Health Bulletin

March 14, 2012

In Today's Issue

  • Medical Doctor Reveals The Shocking Truth
  • New Study Finds Pancreas Can 'Taste' Fructose, Possible Links With Diabetes...
  • The "secret" to losing belly fat...
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New Study Finds Pancreas Can 'Taste' Fructose, Possible Links With Diabetes...

Dear Reader,

Some surprising news on fructose. There's new research, appearing in the Proceedings of the National Academy of Sciences that finds the pancreas has sweet taste receptors like those on the tongue that can actually taste fructose. As you may know, fructose is a part of many processed foods and drinks, even though experts are worried that Americans consume far more fructose than we should.

When we eat, beta cells in the pancreas react to the rise in glucose levels by releasing more insulin. The insulin then attaches to other body cells and opens them up, allowing the glucose to get into the cell and provide energy.

In the study, the team saw that fructose activates sweet taste receptors on beta cells, and this also caused them to release insulin. When both glucose and fructose were encountered, as would happen with foods we eat most often, even more insulin was released.

Too much insulin, or inefficient use of this substance by the body is associated with both type 2 diabetes and obesity. Both conditions are hard on the body and can bring some nasty complications.

The researchers are also fascinated by the idea that the sense of taste isn't just on the tongue, but we have many cells to control how the body handles sugars according to study senior author, Bjorn Tyrberg, an assistant professor and scientific advisor at Florida's Sanford-Burnham Medical Research Institute.

While fructose hasn't been linked to insulin secretion before, this study shows that when the pancreas tastes fructose there is an effect on the secretion of insulin as long as glucose is also present.

It's not clear what affect fructose might have on metabolism. When the research team inactivated the sweet taste receptors on the beta cells, they didn't secrete insulin when exposed to the fructose. This suggests that these receptors may well play a part in metabolic diseases like those mentioned above.

We know that both fructose and glucose are types of sugars. Fructose is a natural part of fruit and honey, but in its concentrated form (high fructose corn syrup) is added to a multitude of processed foods and drinks. The U.S. Food and Drug Administration says fructose is safe and has been well-studied in humans.

Continues below...


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New Study Finds Pancreas Can 'Taste' Fructose, Possible Links With Diabetes... Continued...

With a comment on the research, Dr. Spyros Mezitis, an endocrinologist and clinical investigator at Lenox Hill Hospital agrees that when you eat fructose and glucose together you get even more of an insulin release.

High sugar consumptions may eventually tire out the pancreas, causing the organ not to release insulin at all. If you have type 2 diabetes already, this could hasten the progression of your disease.

Today this is all speculation; human studies need to be done, outside the lab, to understand this connection over time. Of course there's no reason not to watch the amount of fructose you take in on a regular basis. You may want to cut down on (or eliminate) regular soda, lemonade, iced tea and sports drinks, as well as fast food and your use of artificial sweeteners.

Also, since the FDA does not regulate the word "natural" it can appear on a label for a product that is far from natural. Manufacturers can label a product "natural" even when it contains high fructose corn syrup since fructose is a naturally occurring sugar. So beware.

To your good health,

Kirsten Whittaker
Daily Health Bulletin Editor




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Sources:
http://www.medicinenet.com/script/main/art.asp?articlekey=154517

Fructose information center:
http://www.fructose.org/

WebMD info on diabetes:
http://diabetes.webmd.com/default.htm

Mayo Clinic info on high fructose corn syrup:
http://www.mayoclinic.com/health/high-fructose-corn-syrup/AN01588

Bjorn Tyrberg, Ph.D., assistant professor and scientific advisor, histology and cellular imaging, Sanford-Burnham Medical Research Institute, Orlando, FL:
http://www.sanfordburnham.org/Talent/Pages/BjörnTyrberg.aspx

Spyros Mezitis, M.D., endocrinologist and clinical investigator, Lenox Hill Hospital:
http://nyp.org/physician/sgmezitis/

Study abstract, Feb. 7, 2012, Proceedings of the National Academy of Sciences, online:
http://www.pnas.org/content/early/2012/01/31/
1115183109.abstract?sid=a5acd07c-52a9-
4586-a409-0c6204f51934

















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