[DHB] These Common OTC Drugs May Prevent Skin Cancer...

Published: Mon, 07/23/12

Subject: [DHB] These Common OTC Drugs May Prevent Skin Cancer...

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Daily Health Bulletin

July 23, 2012

In Today's Issue

  • 1 Quick Technique To Burn More Fat
  • Prevent Skin Cancer By Taking These Common OTC Drugs...
  • WARNING: The truth about Moles, Warts and Skintags...
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Prevent Skin Cancer By Taking These Common OTC Drugs...

Dear Reader,

Could the painkilling drugs we all commonly use be doing double duty - easing pain and protecting against skin cancer? Taking NSAIDs (nonsteroidal anti-inflammatory drugs) such as aspirin, ibuprofen and naproxen appears to significantly lower the risk for several types of skin cancer according to a new Danish study.

What's even better, the protective effect of both the prescription and nonprescription forms of these medications on skin cancer risk grows stronger the longer you take them. The research appears online in the journal Cancer.

While earlier research has found NSAIDs to offer some protection against cancer (colorectal cancers), past examinations of how these medicines affect skin cancer had some major design problems that made findings questionable.

We do know that these drugs work to fight inflammation, a body process that's known to be a part of the development of cancer in the body or on the skin surface. So for the latest work, the team analyzed prescription databases and health data registries that included the Danish Civil Registration System and the Danish Cancer Registry for the use of NSAIDs and the rates of specific skin cancers.

The team looked at diagnostic and death records that involved almost 2,000 cases of squamous cell cancers, about 13,300 basal cell cancers and almost 3,250 malignant melanomas diagnosed between the years 1991 and 2009. Prescriptions histories were obtained for the cancer patients and almost 179,000 healthy Danish control subjects.

NSAID users were shown to have a reduced risk of three types of skin cancer - malignant melanoma, basal cell carcinoma and squamous cell carcinoma explains study lead, Sigrun Alba Johannesdottir, from the department of clinical epidemiology at Aarhus University Hospital in Denmark. The greatest impact came for squamous cell carcinomas and malignant melanomas, especially if these medications had been taken often and over a long time period.

Of course taking NSAIDs over the long term does come with some risks - stomach bleeding or damage to the kidneys. Doctors typically recommend that patients take these medications at the lowest possible doses and for the shortest period of time. In the research however, participants had been taking high does of prescriptions NSAIDs, often for longer periods.

Continues below...


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Prevent Skin Cancer By Taking These Common OTC Drugs... Continued...

Keep in mind that the study only shows an association between NSAID use and skin cancer, it does not prove that taking these medications protects against this form of cancer. The researchers readily admit that the NSAID-skin cancer connection could be impacted by many lifestyle factors that were not accounted for in the study - things like skin type or sun exposure pattern. But they do hope that these findings will spur more research on skin cancer prevention. The potential benefit should also be made clear to patients when doctors are talking to them about the potential benefits and dangers of NSAID use.

The exciting thing about the research is that it gives people a chance to impact skin cancer risk by doing something that most of us are doing now to manage another condition. You should still talk with your own doctor before starting to take NSAIDs on a regular basis - this is not the right approach for everyone. Your own doctor will be best placed to advise you.

Remember, the most effective protection against skin cancer is to avoid prolonged unprotected exposure to the sun.

To your good health,

Kirsten Whittaker
Daily Health Bulletin Editor




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Sources:
http://news.yahoo.com/common-painkillers-may-help-prevent-skin-cancer-study-160406610.html

More info on NSAIDs:
http://orthoinfo.aaos.org/topic.cfm?topic=a00284

Consumer Reports info on NSAIDs:
http://www.consumerreports.org/health/best-buy-drugs/nsaids.htm

Skincancer.org info on skin cancer:
http://www.skincancer.org/

National Cancer Institute NSAIDs and cancer:
http://seer.cancer.gov/studies/epidemiology/study17.html

Study abstract, online in the journal Cancer, published online May 29, 2012:
http://onlinelibrary.wiley.com/doi/10.1002/cncr.27406/abstract













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