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In Today's Issue
- Announcing: Doctor Approved Store Cupboard Remedies that Really Work...
- To Know If You Have High Cholesterol
- The Healthy Back Institute's Back Pain Relief Journal
Announcing: Doctor Approved Store Cupboard Remedies that Really Work...
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To Know If You Have High Cholesterol
Dear Reader,
If you have high cholesterol, you probably know what statin drugs are, you may even be taking one. These medications are widely prescribed drugs that bring down cholesterol and thus hold off heart disease in those who have diabetes, metabolic syndrome or are obese, however, researchers from the University of Missouri, MU for short, have found that the drug simvastatin (Zocor) hindered the benefits of exercise for adults who were either obese or overweight.
Statins have been in use for 15 to 20 years, so the impact on aerobic fitness and overall health are still unknown. Many cardiologists choose to prescribe statin drugs to all their patients over a set age, whether they have metabolic syndrome or not. The medications are also a choice for those with type 2 diabetes. Associate professor of nutrition and exercise physiology at MU, Dr. John Thyfault thinks that professionals should more closely examine the risks and benefits to patients of using these drugs given the new data on how they can affect exercise training.
Fitness has been shown to be the best predictor of longevity because it protects people from so many dangerous and debilitating chronic diseases. Daily physical activity is what's needed to keep fit, and get in on those positive health outcomes. Thyfault believes that if statin drugs cause complications to improving or maintaining fitness levels, not all patients should be taking them.
Thyfault and his colleagues assessed the cardiorespiratory fitness of 37 previously sedentary obese people who were from 25 to 59 years old and had low fitness levels. The subjects all followed a 12-week exercise regimen on the MU campus, and 18 of the subjects were taking 40 mg of simvastatin each day. Those who only exercised upped their cardiorespiratory fitness by an average of 10% compared to the 1.5% increase of those who were taking statins and exercising.
Continues below...
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To Know If You Have High Cholesterol Continued...
Then there's this - skeletal muscle mitochondrial content, where muscles turn
oxygen into energy, decreased by 4.5% for those taking statins, compared to a
13% increase in the exercise only group.
Keep in mind that your need for a statin drug also depends on the other risk factors that you have for heart disease. If your only risk factor for heart disease is high cholesterol numbers, then statin drugs may not be right for you. When prescribing, your doctor will consider family history of heart disease, if you live an inactive lifestyle, if you have high blood pressure or diabetes, if you're not in good health, are overweight or obese, if you smoke or have narrowing or the arteries in your neck, arms or legs.
Future work in this area will need to see if lower doses of simvastatin (or other statin drugs) have the same affect on exercise outcomes. Also, starting a statin dug after exercising and thus being more fit might lessen the impact on fitness Thyfault suggests. In the meantime, if you have high cholesterol and are taking medications, don't stop just because of this latest work. Your own medical situation is unique and you should discuss any concerns you have about these medications with your doctor.
To your good health,
Kirsten Whittaker
Daily Health Bulletin Editor
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Sources:
http://www.medicalnewstoday.com/releases/260621.php
Mayo Clinic info on statins:
http://www.mayoclinic.com/health/statins/CL00010
Home page of the University of Missouri, MU for short:
http://www.missouri.edu
News release, MU, May 15, 2013:
http://munews.missouri.edu/news-releases/2013/0515-cholesterol-lowering-drug-may-reduce-exercise-benefits-for-obese-adults-mu-study-finds/
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